Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling | BMC Cancer | Full Text
Phase II Study of Obatoclax Mesylate (GX15-070), a Small-Molecule BCL-2 Family Antagonist, for Patients With Myelofibrosis - Clinical Lymphoma, Myeloma and Leukemia
Obatoclax induced autophagy leads to cell death. (A) A time course... | Download Scientific Diagram
The pan-Bcl-2 inhibitor obatoclax promotes differentiation and apoptosis of acute myeloid leukemia cells | SpringerLink
Drugs and Clinical Approaches Targeting the Antiapoptotic Protein: A Review
Lapatinib and obatoclax treatment induces an ER stress response that... | Download Scientific Diagram
Dual mTORC1/2 inhibition compromises cell defenses against exogenous stress potentiating Obatoclax-induced cytotoxicity in atypical teratoid/rhabdoid tumors | Cell Death & Disease
Obatoclax - an overview | ScienceDirect Topics
Obatoclax Induces G1/G0‐Phase Arrest via p38/p21waf1/Cip1 Signaling Pathway in Human Esophageal Cancer Cells - Zhong - 2014 - Journal of Cellular Biochemistry - Wiley Online Library
IJMS | Free Full-Text | Obatoclax, a Pan-BCL-2 Inhibitor, Targets Cyclin D1 for Degradation to Induce Antiproliferation in Human Colorectal Carcinoma Cells | HTML
IJMS | Free Full-Text | Obatoclax, a Pan-BCL-2 Inhibitor, Targets Cyclin D1 for Degradation to Induce Antiproliferation in Human Colorectal Carcinoma Cells | HTML
Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and BAX/BAK | Cell Death & Disease
Phase I study of obatoclax mesylate (GX15-070), a small molecule pan–Bcl-2 family antagonist, in patients with advanced chronic lymphocytic leukemia - ScienceDirect
Randomized phase II study of carboplatin and etoposide with or without obatoclax mesylate in extensive-stage small cell lung cancer - Lung Cancer
Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis | PNAS
The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their Alkalinization | PLOS ONE