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Obatoclax - Wikipedia
Obatoclax - Wikipedia

Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in  colorectal cancer cells independent of canonical autophagy signaling | BMC  Cancer | Full Text
Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling | BMC Cancer | Full Text

Obatoclax Mesylate (GX15-070) | ≥99%(HPLC) | Selleck | Bcl-2 antagonist
Obatoclax Mesylate (GX15-070) | ≥99%(HPLC) | Selleck | Bcl-2 antagonist

OBATOCLAX
OBATOCLAX

803712-79-0 Obatoclax mesylate AKSci V2454
803712-79-0 Obatoclax mesylate AKSci V2454

Pharmacodynamic biomarker analysis from the phase 1 trial of obatoclax... |  Download Scientific Diagram
Pharmacodynamic biomarker analysis from the phase 1 trial of obatoclax... | Download Scientific Diagram

Obatoclax mesylate (GX15-070) | C21H23N3O4S - PubChem
Obatoclax mesylate (GX15-070) | C21H23N3O4S - PubChem

Obatoclax mesylate | C21H23N3O4S - PubChem
Obatoclax mesylate | C21H23N3O4S - PubChem

Phase II Study of Obatoclax Mesylate (GX15-070), a Small-Molecule BCL-2  Family Antagonist, for Patients With Myelofibrosis - Clinical Lymphoma,  Myeloma and Leukemia
Phase II Study of Obatoclax Mesylate (GX15-070), a Small-Molecule BCL-2 Family Antagonist, for Patients With Myelofibrosis - Clinical Lymphoma, Myeloma and Leukemia

Obatoclax induced autophagy leads to cell death. (A) A time course... |  Download Scientific Diagram
Obatoclax induced autophagy leads to cell death. (A) A time course... | Download Scientific Diagram

The pan-Bcl-2 inhibitor obatoclax promotes differentiation and apoptosis of  acute myeloid leukemia cells | SpringerLink
The pan-Bcl-2 inhibitor obatoclax promotes differentiation and apoptosis of acute myeloid leukemia cells | SpringerLink

Drugs and Clinical Approaches Targeting the Antiapoptotic Protein: A Review
Drugs and Clinical Approaches Targeting the Antiapoptotic Protein: A Review

Lapatinib and obatoclax treatment induces an ER stress response that... |  Download Scientific Diagram
Lapatinib and obatoclax treatment induces an ER stress response that... | Download Scientific Diagram

Dual mTORC1/2 inhibition compromises cell defenses against exogenous stress  potentiating Obatoclax-induced cytotoxicity in atypical teratoid/rhabdoid  tumors | Cell Death & Disease
Dual mTORC1/2 inhibition compromises cell defenses against exogenous stress potentiating Obatoclax-induced cytotoxicity in atypical teratoid/rhabdoid tumors | Cell Death & Disease

Obatoclax - an overview | ScienceDirect Topics
Obatoclax - an overview | ScienceDirect Topics

Obatoclax Induces G1/G0‐Phase Arrest via p38/p21waf1/Cip1 Signaling Pathway  in Human Esophageal Cancer Cells - Zhong - 2014 - Journal of Cellular  Biochemistry - Wiley Online Library
Obatoclax Induces G1/G0‐Phase Arrest via p38/p21waf1/Cip1 Signaling Pathway in Human Esophageal Cancer Cells - Zhong - 2014 - Journal of Cellular Biochemistry - Wiley Online Library

IJMS | Free Full-Text | Obatoclax, a Pan-BCL-2 Inhibitor, Targets Cyclin D1  for Degradation to Induce Antiproliferation in Human Colorectal Carcinoma  Cells | HTML
IJMS | Free Full-Text | Obatoclax, a Pan-BCL-2 Inhibitor, Targets Cyclin D1 for Degradation to Induce Antiproliferation in Human Colorectal Carcinoma Cells | HTML

IJMS | Free Full-Text | Obatoclax, a Pan-BCL-2 Inhibitor, Targets Cyclin D1  for Degradation to Induce Antiproliferation in Human Colorectal Carcinoma  Cells | HTML
IJMS | Free Full-Text | Obatoclax, a Pan-BCL-2 Inhibitor, Targets Cyclin D1 for Degradation to Induce Antiproliferation in Human Colorectal Carcinoma Cells | HTML

Obatoclax mesylate Supplier | CAS 803712-79-0 | GX15-070 | Tocris Bioscience
Obatoclax mesylate Supplier | CAS 803712-79-0 | GX15-070 | Tocris Bioscience

Obatoclax - an overview | ScienceDirect Topics
Obatoclax - an overview | ScienceDirect Topics

Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and  BAX/BAK | Cell Death & Disease
Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and BAX/BAK | Cell Death & Disease

Phase I study of obatoclax mesylate (GX15-070), a small molecule pan–Bcl-2  family antagonist, in patients with advanced chronic lymphocytic leukemia -  ScienceDirect
Phase I study of obatoclax mesylate (GX15-070), a small molecule pan–Bcl-2 family antagonist, in patients with advanced chronic lymphocytic leukemia - ScienceDirect

Randomized phase II study of carboplatin and etoposide with or without  obatoclax mesylate in extensive-stage small cell lung cancer - Lung Cancer
Randomized phase II study of carboplatin and etoposide with or without obatoclax mesylate in extensive-stage small cell lung cancer - Lung Cancer

Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes  MCL-1-mediated resistance to apoptosis | PNAS
Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis | PNAS

The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their  Alkalinization | PLOS ONE
The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their Alkalinization | PLOS ONE

Obatoclax Mesylate (GX15-070) | ≥99%(HPLC) | Selleck | Bcl-2 antagonist
Obatoclax Mesylate (GX15-070) | ≥99%(HPLC) | Selleck | Bcl-2 antagonist